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Methods for preparation of biocompatible polymer based apixaban loaded microsphere

机译:基于生物相容性聚合物的载有阿哌沙班的微球的制备方法

摘要

The present invention relates to a method for manufacturing biocompatible polymer-based apixaban-containing microspheres. Specifically, in the method for manufacturing biocompatible polymer-based apixaban-containing microspheres, the present invention relates to the method for manufacturing biocompatible polymer-based apixaban-containing microspheres, which comprises following steps of: i) adding a fatty acid or triglyceride to a dispersion phase; and ii) preparing microspheres by a microfluidic method. The method for manufacturing biocompatible polymer-based apixaban-containing microspheres of the present invention can be usefully used for manufacturing microspheres in which a high content of apixaban is stably enclosed.
机译:本发明涉及一种用于制造基于生物相容性聚合物的含阿哌沙班的微球的方法。具体地,在用于制造基于生物相容性聚合物的含阿哌沙班的微球的方法中,本发明涉及用于制造基于生物相容性聚合物的含阿哌沙班的微球的方法,该方法包括以下步骤:i)将脂肪酸或甘油三酸酯添加到其中。分散相ii)通过微流体方法制备微球。本发明的含有生物相容性聚合物的含阿哌沙班的微球的制造方法可用于稳定地封入高含量的阿哌沙班的微球的制造。

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