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METHODS AND SYSTEMS FOR SEQUENCING CELL-FREE MICROBIOME DNA
METHODS AND SYSTEMS FOR SEQUENCING CELL-FREE MICROBIOME DNA
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机译:测序无细胞微生物DNA的方法和系统
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摘要
The present disclosure provides methods, systems, kits, and compositions for enriching cell-free DNA of a microbiome from a collection of cell-free DNA that includes host cell-free DNA. Such methods and systems may provide for more efficient and economical approaches for analyzing microbiome cell-free DNA by excluding at least some portion of host cell-free DNA from a common collection of cell-free DNA. The microbiome cell-free DNA may be enriched by size selection, by a reduction in the amount of linear DNA, and/or by targeting protein(s) to which host cell-free DNA may be associated.
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