首页> 外国专利> BRANCHED-BLOCK COPOLYMER PHOTO-CROSSLINKER FUNCTIONALIZED WITH PHOTOREACTIVE GROUPS AND ITS USE FOR SHAPING DEGRADABLE PHOTO-CROSSLINKED ELASTOMERS SUITABLE FOR MEDICAL AND TISSUE-ENGINEERING APPLICATIONS

BRANCHED-BLOCK COPOLYMER PHOTO-CROSSLINKER FUNCTIONALIZED WITH PHOTOREACTIVE GROUPS AND ITS USE FOR SHAPING DEGRADABLE PHOTO-CROSSLINKED ELASTOMERS SUITABLE FOR MEDICAL AND TISSUE-ENGINEERING APPLICATIONS

机译：具有光活性基团的支链嵌段共聚物光交联剂及其在塑形可降解光交联弹性体中的应用，可用于医学和组织工程应用

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摘要

The present invention relates to novel degradable branched-blockcopolymers, comprising a star-shaped copolymer central core or a linear copolymer central core, functionalized with photoreactive groups chosen among aryl-azide, (meth)acrylate or thiol groups. The present invention also relates to the use of these degradable branched-block copolymers as photo- crosslinkersto provide degradable photo-crosslinkedelastomers as biomaterials suitable for medical and tissue engineering applications. A method for preparinga degradable photo- crosslinked polymer, preferably a degradable photo-crosslinked elastomer,starting from the branched-block copolymer of the invention via a shaping process and an irradiation step is also provided.

机译：本发明涉及新型的可降解的支链嵌段共聚物，其包括星形化合物中心核或线性共聚物中心核，其被选自芳基叠氮化物，（甲基）丙烯酸酯或硫醇基的光反应性基团官能化。本发明还涉及这些可降解的支链嵌段共聚物作为光交联剂的用途，以提供可降解的光交联的弹性体作为适用于医学和组织工程应用的生物材料。还提供了一种从本发明的支链嵌段共聚物经成型过程和辐照步骤开始制备可降解的光交联聚合物，优选地可降解的光交联弹性体的方法。

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公开/公告号WO2020144236A1

专利类型
公开/公告日2020-07-16

原文格式PDF
申请/专利权人 UNIVERSITE DE MONTPELLIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER;UNIVERSITE DE GRENOBLE ALPES;INSTITUT POLYTECHNIQUE DE GRENOBLE;
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申请/专利号WO2020EP50325
发明设计人 GARRIC XAVIER;BOSSARD FRÉDÉRIC;GANGOLPHE LOUIS;NOTTELET BENJAMIN;
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申请日2020-01-08
分类号C08G65/26;C08G65/333;C08G63/664;
国家 WO
入库时间 2022-08-21 11:10:12

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