首页> 外国专利> USE OF CYSTATIN SN IN DETECTING CHRONIC RHINOSINUSITIS WITH NASAL POLYPS SUBTYPE AND PREDICTING SENSITIVITY OF PATIENT TO GLUCOCORTICOID

USE OF CYSTATIN SN IN DETECTING CHRONIC RHINOSINUSITIS WITH NASAL POLYPS SUBTYPE AND PREDICTING SENSITIVITY OF PATIENT TO GLUCOCORTICOID

机译:胱抑素SN在鼻息肉亚型慢性鼻窦炎中的应用及对糖皮质激素敏感性的预测。

摘要

Provided in the present invention are a kit for detecting chronic rhinosinusitis with nasal polyps subtype, and the use of a CST1 gene as a biomarker and a method for detecting chronic rhinosinusitis with nasal polyps subtype. The CST1 gene, as a biomarker, can detect chronic rhinosinusitis with nasal polyps subtype or predict the sensitivity of a patient with chronic rhinosinusitis with nasal polyps to glucocorticoid. The detection method comprises PCR using specific primers of the CST1 gene, such as real-time fluorescence quantitative PCR, so as to detect the expression amount of the CST1 gene.
机译:本发明提供了一种用于检测具有鼻息肉亚型的慢性鼻-鼻窦炎的试剂盒,以及CST1基因作为生物标记物的用途和用于检测具有鼻息肉亚型的慢性鼻-鼻窦炎的方法。 CST1基因作为一种生物标记物,可以检测出具有鼻息肉亚型的慢性鼻-鼻窦炎或预测患有鼻息肉的慢性鼻-鼻窦炎患者对糖皮质激素的敏感性。检测方法包括使用CST1基因的特异性引物的PCR,例如实时荧光定量PCR,以检测CST1基因的表达量。

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