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首页> 外国专利> IMPROVED QUANTAMATRIX ASSAY PLATFORM-BASED, DIAGNOSTIC METHOD CAPABLE OF SIMULTANEOUSLY IDENTIFYING DETECTION OF MYCOBACTERIUM TUBERCULOSIS AND RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS TO RIFAMPIN, ISONIAZID, ETHAMBUTOL, QUINOLONE, SECOND LINE INJECTABLE DRUGS SUCH AS AMIKACIN, KANAMYCIN, AND CAPEOMYCIN, AND STREPTOMYCIN DRUGS, AND KIT THEREFOR

IMPROVED QUANTAMATRIX ASSAY PLATFORM-BASED, DIAGNOSTIC METHOD CAPABLE OF SIMULTANEOUSLY IDENTIFYING DETECTION OF MYCOBACTERIUM TUBERCULOSIS AND RESISTANCE OF MYCOBACTERIUM TUBERCULOSIS TO RIFAMPIN, ISONIAZID, ETHAMBUTOL, QUINOLONE, SECOND LINE INJECTABLE DRUGS SUCH AS AMIKACIN, KANAMYCIN, AND CAPEOMYCIN, AND STREPTOMYCIN DRUGS, AND KIT THEREFOR

机译：基于改进的量子矩阵分析平台的诊断方法，能够同时鉴定结核分枝杆菌的结核分枝杆菌，以及对结核分枝杆菌对利福平，异烟肼，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇，肌醇和肌醇那个

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摘要

The present invention relates to an improved QuantaMatrix assay platform-based, diagnostic method capable of simultaneously identifying the detection of Mycobacterium tuberculosis and nontuberculous mycobacteria and the resistance of Mycobacterium tuberculosis to rifampin, isoniazid, ethambutol, quinolone, second line injectable drugs (KM, AMK, CAP), and streptomycin drugs, and a kit therefor. The present invention can reduce a time taken to separate and culture bacteria from a specimen in a drug resistance test and can conduct an effective drug sensitive test of multiple drug-resistant and extensively drug-resistant Mycobacterium tuberculosis in multiple specimens, whereby accurate and fast selection can be made of an anti-tuberculous agent in the treatment of tuberculosis patients, so that the present invention can be advantageously used for early treatment and infection spread prevention. In addition, the present invention can prevent the misdiagnosis and prescription errors that may be caused by the contamination or combined infection of nontuberculous mycobacteria.
机译：本发明涉及一种改进的基于QuantaMatrix测定平台的诊断方法，该方法能够同时鉴定结核分枝杆菌和非结核分枝杆菌的检测以及结核分枝杆菌对利福平，异烟肼，乙胺丁醇，喹诺酮，二线可注射药物（KM，AMK）的抗性。 （CAP）和链霉素药物及其试剂盒。本发明可以减少在耐药性测试中从样本分离和培养细菌所花费的时间，并且可以对多个样本中的多种耐药性和广泛耐药性结核分枝杆菌进行有效的药物敏感性测试，从而准确而快速地选择在结核病患者的治疗中，可以使用抗结核药制成药物，因此本发明可以有利地用于早期治疗和预防感染扩散。另外，本发明可以防止由非结核分枝杆菌的污染或合并感染引起的误诊和处方错误。

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