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Particle Vaccine Formulations for Induction of Innate and Adaptive Immunity
Particle Vaccine Formulations for Induction of Innate and Adaptive Immunity
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机译：用于诱导先天和适应性免疫的颗粒疫苗配方
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摘要
Disclosed are compositions, kits, and methods for inducing an immune response against an infection or a disease. The compositions typically include biodegradable particles having an average effective diameter of 0.5 - 20 µm, and optionally the compositions include one or more of an adjuvant, an apoptosis inhibitor, and an antigen. The compositions, kits, and methods may be utilized to induce a cell-mediated response, such as a T-helper cell response, and/or a humoral response against a pathogen or a disease. In some embodiments, the compositions, kits, and methods may be utilized to induce preferentially a Th1 response versus other types of immune responses such as a Th2 response.
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