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(S)-CSA SALT OF S-KETAMINE, (R)-CSA SALT OF S-KETAMINE AND PROCESSES FOR THE PREPARATION OF S-KETAMINE

机译:S-酮的(S)-CSA盐,S-酮的(R)-CSA盐及其制备方法

摘要

The present invention is directed to processes for the preparation of esketamine. The present invention is liirther directed to processes for the resolution of S-ketamine from a racemic or enantiomerically enriched mixture of ketamine. The present invention is further directed to an (S)-CSA salt of S-ketamine, more particularly a monohydrate form of the (S)-CSA salt of S-ketamine; and to an (R)-CSA salt of R-ketamine.
机译:本发明涉及制备艾氯胺酮的方法。本发明还涉及从外消旋或对映体富集的氯胺酮中拆分S-氯胺酮的方法。本发明进一步涉及S-氯胺酮的(S)-CSA盐,更特别地涉及S-氯胺酮的(S)-CSA盐的一水合物形式。以及R-氯胺酮的(R)-CSA盐。

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