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首页> 外国专利> COMBINATION OF SPECIFIC DNA SEQUENCES SELF-ASSEMBLED IN THE SHAPE OF ROMANIA'S MAP

COMBINATION OF SPECIFIC DNA SEQUENCES SELF-ASSEMBLED IN THE SHAPE OF ROMANIA'S MAP

机译：罗马尼亚地图形状中自组装的特定DNA序列的组合

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The invention relates to a specific combination of short synthetic single-stranded DNA sequences that determine the folding of a third long single-stranded DNA sequence in a structure having the shape of Romania's map, useful in the field of biotechnologies. The specific sequences consist of 162 single-stranded DNA staple sequences having dimensions of 20-63 nitrogenous bases per sequence which are self-assembled with the DNA scaffold sequence of the M13mp18 bacteriophage under reaction conditions. The result is a structure in the shape of Romania's borders at the nanometric level as visualized by atomic force microscopy.
机译：本发明涉及短合成单链DNA序列的特定组合，其确定第三长单链DNA序列在具有罗马尼亚图谱形状的结构中的折叠，这在生物技术领域中是有用的。特定序列由162个单链DNA钉序列组成，每个序列的大小为20-63个含氮碱基，它们在反应条件下与M13mp18噬菌体的DNA支架序列自组装。结果是通过原子力显微镜观察到的纳米级罗马尼亚边界形状的结构。

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