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SYSTEMS AND METHODS FOR GENERATING AN ELASTOGRAM OF BRAIN TISSUE USING MESOSCOPIC WAVELENGTH ULTRASOUND

机译:使用介观波长超声产生脑组织弹性图像的系统和方法

摘要

Methods, systems, and devices for mechanically disturbing tissues of the central nervous system including a brain of a subject are provided. An elastogram of brain tissue may be generated using mesoscopic wavelength ultrasound composed of longitudinal waves in brain tissues to produce micromechanical disturbances of brain nuclei and circuits for characterization of their mechanical properties (e.g., stiffness, elasticity, rigidity, viscoelasticity). A magnetic resonance elastography (MRE) system includes an MRE engine in electronic communication with at least one transducer and with a magnetic resonance imaging (MRI) device. The MRE engine is configured to electronically control operation of the at least one transducer to emit ultrasound, to electronically receive, from the MRI device, at least one signal indicative of measurements of displacement of the brain tissue by the ultrasound, and to electronically generate an elastogram of the brain tissue based on the at least one signal.
机译:提供了用于机械地扰动包括对象的大脑的中枢神经系统的组织的方法,系统和设备。可以使用由脑组织中的纵波组成的介观波长超声来产生脑组织的弹性图,以产生脑核和电路的微机械扰动,以表征其机械特性(例如,刚度,弹性,刚度,粘弹性)。磁共振弹性成像(MRE)系统包括与至少一个换能器和磁共振成像(MRI)设备电子通信的MRE引擎。 MRE引擎被配置为电子控制至少一个换能器的操作以发射超声,从MRI设备电子接收至少一个指示通过超声对脑组织的位移的测量的信号,并且电子地产生超声信号。基于至少一个信号的脑组织的弹性成像。

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