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ISOLATION AND CHARACTERIZATION OF PORCINE SAPELOVIRUS STRAIN
ISOLATION AND CHARACTERIZATION OF PORCINE SAPELOVIRUS STRAIN
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机译：猪沙门氏病毒菌株的分离和鉴定
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摘要
The present invention is directed to novel nucleotide and amino acid sequences of Porcine Sapelovirus (“PSV”), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine PSV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include polynucleotide constructs that replicate in tissue culture and in host swine. The invention also provides for novel full-length PSV genomes that can replicate efficiently in host animals and tissue culture.
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