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Automatic Generation of User and Non-User Cohorts for The Estimation of Drug's Effect from Longitudinal Observational Data
Automatic Generation of User and Non-User Cohorts for The Estimation of Drug's Effect from Longitudinal Observational Data
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机译：自动生成用户和非用户群组，以根据纵向观察数据估算药物的作用
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摘要
Embodiments of the present systems and methods may provide generation of user and non-user cohorts for the estimation of drug's effect from longitudinal observational data that provide reduction of biases, account for progression of disease over time, and improve statistical significance. For example, in an embodiment, a computer-implemented method for conducting an observational trial of a drug under study may comprise receiving data relating to a plurality of patients, the data including drug prescription information for each patient, assigning each of the plurality of patients to a trial cohort based on the drug prescription information, setting an index date for each of the plurality of patients, and conducting an observational drug trial using the generated cohorts and index dates.
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