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Method and System for Post-Traumatic Stress Disorder (PTSD) and mild Traumatic Brain Injury (mTBI) Diagnosis Using Magnetic Resonance Spectroscopy
Method and System for Post-Traumatic Stress Disorder (PTSD) and mild Traumatic Brain Injury (mTBI) Diagnosis Using Magnetic Resonance Spectroscopy
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机译:使用磁共振波谱诊断创伤后应激障碍(PTSD)和轻度创伤性脑损伤(mTBI)的方法和系统
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摘要
A MRS (magnetic resonance spectroscopy or nuclear magnetic resonance NMR)-based PTSD (post-traumatic stress disorder) and mTBI (mild traumatic brain injury) diagnostic system and method uses MRS signals, already pre-processed by the MRS scanner software. The signals are collected in vivo from specific regions of the brain. A wavelet decomposition is applied to the MRS signals, and the amplitude of the wavelet coefficients and their location in the MRS signals are used as features for training diagnostic classifiers of disease states. These classifiers are identified through analysis of features of individuals whose health status is known. Once the classifiers are trained, patients can be diagnosed by using the same wavelet features extracted from in vivo MRS scans of their brain regions.
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