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Methods for Identifying a Companion Animal Susceptible to Treatment That Reduces the Risk of Stone Formation and Compositions for Reducing Such Risk

机译:识别易于接受治疗的伴侣动物的方法,可减少结石形成的风险以及降低此类风险的成分

摘要

Methods of analyzing a biological sample obtained from the feline subject for the presence of two copies of major allele G of SNP A1_212891692 and/or to the concentration of betaine and/or 2-oxoarginine in the sample are disclosed. The methods are used in methods to identify a feline subject that would benefit from a treatment that reduces risk of calcium oxalate stone formation and in methods of treating a feline subject to reduce risk of calcium oxalate stone formation The treatment on comprises administering to the feline subject a composition that comprises an effective amount of one or more of ingredients selected from the group consisting of betaine, green tea, fenugreek and tulsi. Feline food composition that comprise effective amounts of betaine, green tea, fenugreek and tulsi are disclosed.
机译:公开了分析从猫科动物获得的生物学样品中存在两个拷贝的SNP A1_212891692的主要等位基因G和/或样品中甜菜碱和/或2-氧精氨酸浓度的方法。所述方法用于鉴定可从降低草酸钙结石形成风险的治疗中受益的猫科动物的方法,以及用于治疗猫草酸形成结石风险降低的猫科动物的治疗方法。治疗包括向猫科动物给药包含有效量的一种或多种选自甜菜碱,绿茶,胡芦巴和塔尔西的成分的组合物。公开了包含有效量的甜菜碱,绿茶,胡芦巴和图尔西的猫科食物组合物。

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