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System and Method for Multi-Color Laser Imaging and Ablation of Cancer Cells Using Fluorescence

机译:利用荧光进行癌细胞多色激光成像和消融的系统和方法

摘要

A fluorescence imaging device detects fluorescence in parts of the visible and invisible spectrum, and projects the fluorescence image directly on the human body, as well as on a monitor, with improved sensitivity, video frame rate and depth of focus, and enhanced capabilities of detecting distribution and properties of multiple fluorophores. Direct projection of three-dimensional visible representations of fluorescence on three-dimensional body areas advantageously permits view of it during surgical procedures, including during cancer removal, reconstructive surgery and wound care, etc. A NIR laser and a human visible laser (HVL) are aligned coaxially and scanned over the operating field of view. When the NIR laser passes over the area where the fluorescent dye is present, it energizes the dye which emits at a shifted NIR frequency detected by a photo diode. The HVL is turned on when emission is detected, providing visual indication of those positions.
机译:荧光成像设备可检测可见光谱和不可见光谱中的荧光,并将荧光图像直接投射到人体以及监视器上,从而提高了灵敏度,视频帧频和焦点深度,并增强了检测能力荧光团的分布和性质。将荧光的三维可见表示形式直接投影在三维人体区域上,有利于在外科手术过程中进行观察,包括在癌症切除,重建手术和伤口护理等过程中。近红外激光和人类可见激光(HVL)同轴对准并在操作视场上扫描。当NIR激光穿过存在荧光染料的区域时,它会激发以以光电二极管检测到的偏移NIR频率发射的染料。当检测到发射时,将打开HVL,以可视方式指示这些位置。

著录项

  • 公开/公告号US2019343392A1

    专利类型

  • 公开/公告日2019-11-14

    原文格式PDF

  • 申请/专利权人 ACCUVEIN INC.;

    申请/专利号US201916512689

  • 申请日2019-07-16

  • 分类号A61B5;A61B18/20;

  • 国家 US

  • 入库时间 2022-08-21 11:23:08

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