首页> 外国专利> All-Natural Drink Composition for Synthesizing and Regenerating Adenosine Triphosphate (ATP) in Muscle Cells and Neurons, Repairing Exercise-Induced Muscle Fiber Damage, Repletion of Glycogen Stores in the Muscle and Liver, Enhancing Blood Flow to Tissue during Intense Exercise, and Preventing and Reducing Oxidative Damage to Tissues during Exercise with Minimal Gastrointestinal Disturbances

All-Natural Drink Composition for Synthesizing and Regenerating Adenosine Triphosphate (ATP) in Muscle Cells and Neurons, Repairing Exercise-Induced Muscle Fiber Damage, Repletion of Glycogen Stores in the Muscle and Liver, Enhancing Blood Flow to Tissue during Intense Exercise, and Preventing and Reducing Oxidative Damage to Tissues during Exercise with Minimal Gastrointestinal Disturbances

机译：全天然饮料组合物，用于在肌肉细胞和神经元中合成和再生三磷酸腺苷（ATP），修复运动引起的肌纤维损伤，补充肌肉和肝脏中糖原的含量，在激烈运动中增强组织的血流量以及预防和预防减少运动对胃肠道干扰的最小氧化损伤

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The present invention provides for a nutritional composition in a liquid drink form, dry powder form, gel form, or carrier form intended to optimize human physiological performance during intense exercise and subsequently return the body to its healthy, pre-exercise state. The composition comprises a carbohydrate and a protein, and preferably a ratio of the carbohydrate to the protein is greater than about 4.3 parts by weight carbohydrate to 1 part by weight protein. Preferably, the liquid nutritional composition is comprised of: (1) carbohydrate in the range of 3.45-10% by weight of the liquid nutritional composition to allow immediate and long-term energy production by muscle cells and neurons, insulin modulation, and muscle glycogen sparing, the carbohydrate being in the form of monosaccharides or polysaccharides or a combination thereof, and the saccharides preferably comprising 40-95% dextrose by weight of the final volume of saccharides, 5-45% fructose by weight of the final volume of saccharides, and 1-25% glucose polymer by weight of the final volume of saccharides; (2) a protein source that contains all 20 “standard” amino acids, in the range of 0.1-0.8% by weight of the liquid nutritional composition, whose inherent structure plus further chemical modification results in amino acid absorption into the bloodstream rapid enough for initiating and enhancing protein synthesis and subsequent muscle cell repair during the exercise and post-exercise periods; (3) Branched-Chain Amino Acids (BCAA), leucine, isoleucine, valine, for use by muscle cells for energy thus sparing glycogen stores, for increasing protein synthesis by stimulating insulin and growth hormone release, and for reducing protein degradation; (4) precursors of the signaling molecule nitric oxide, important for increasing blood flow and subsequent nutrient delivery (including those in this composition) to tissue during intense exercise; (5) precursors of creatine, a molecule important for ATP regeneration in muscle and nerve cells and for muscle cell volumizing effects; (6) a mixture of hydrophilic and hydrophobic antioxidants: retinol/Beta-carotene (Vitamin A), ascorbic acid (Vitamin C), and di-alpha-tocopheryl acetate (Vitamin E); ubiquinone (coenzyme Q₁₀[5-100 mg/500 ml], which in addition to its antioxidant properties is also important for ATP generation and Vitamin E regeneration; a mixture of 10-100 mg epigallocatechin gallate (EGCG) and 25-150 mg polyphenols from green tea extract; 40-250 mg ellagic acid and punicalagin from pomegranate or raspberry extract, at ratios comparable to that found in the whole fruit, which have been shown to have protective effects on blood vessels as well as inhibiting stimulation of the pro-inflammatory protein interleukin-1b (IL-b) which causes degradation and damage to joints (These six antioxidants prevent and eradicate reactive oxygen species and free radicals generated during strenuous exercise, thus preserving muscle integrity.); and (7) the ions Na+, Cl−, K+, Ca+2, Mg+², and Zn+², which are important for the muscle fiber contraction and relaxation cycle, for neuronal signal propagation, for repletion of such ions lost in excessive perspiration during exercise, for water absorption in the gastrointestinal tract, and for catalytic action by energy producing and antioxidant enzymes.

机译：本发明提供了液体饮料形式，干粉形式，凝胶形式或载体形式的营养组合物，旨在在剧烈运动中优化人的生理性能，并随后使身体恢复其健康，运动前的状态。该组合物包含碳水化合物和蛋白质，并且优选地，碳水化合物与蛋白质的比率大于约4.3重量份的碳水化合物与1重量份的蛋白质。优选地，液体营养组合物包含：（1）碳水化合物，占液体营养组合物重量的3.45-10％，以允许肌肉细胞和神经元立即和长期产生能量，胰岛素调节和肌肉糖原保留，碳水化合物为单糖或多糖或其组合的形式，并且糖优选包含按糖的最终体积计重量的40-95％的葡萄糖，按糖的最终体积计重量的5-45％的果糖，和按糖的最终体积的重量计1-25％的葡萄糖聚合物; （2）包含所有20种“标准”氨基酸的蛋白质源，其含量占液态营养成分的0.1-0.8％（重量），其固有结构加上进一步的化学修饰导致氨基酸迅速吸收到血流中，从而足以在运动和运动后时期，开始并增强蛋白质的合成以及随后的肌肉细胞修复; （3）支链氨基酸（BCAA），亮氨酸，异亮氨酸，缬氨酸，用于肌肉细胞提供能量，从而节省糖原存储，通过刺激胰岛素和生长激素释放来增加蛋白质合成，并减少蛋白质降解; （4）信号分子一氧化氮的前体，对于在激烈运动中增加血流量和随后的营养向组织的输送（包括该组合物中的那些）很重要; （5）肌酸的前体，肌酸是对肌肉和神经细胞中ATP再生和肌肉细胞富集作用重要的分子; （6）亲水和疏水抗氧化剂的混合物：视黄醇/β-胡萝卜素（维生素A），抗坏血酸（维生素C）和乙酸二α-生育酚酯（维生素E）;泛醌（辅酶Q _{10 [5-100 mg / 500 ml]，除具有抗氧化特性外，对于ATP的产生和维生素E的再生也很重要;表没食子儿茶素没食子酸酯10-100 mg的混合物（ EGCG）和25-150 mg绿茶提取物中的多酚; 40-250 mg石榴酸或石榴提取物中的鞣花酸和punicalagin，其比例与整个水果中所发现的比例相当，已显示出对血管具有保护作用，例如以及抑制促炎蛋白白介素-1（I> b （IL-b）的刺激，后者会导致关节降解和损伤（这六种抗氧化剂可预防和消除剧烈运动中产生的活性氧和自由基，从而保持肌肉的完整性。）;以及（7）Na +，Cl-，K +，Ca + 2，Mg + ^{2 和Zn + ^{2 肌肉纤维的收缩和松弛周期，用于神经元信号的传播，用于补充过多损失的离子运动中排汗，胃肠道吸水，能量产生和抗氧化酶的催化作用。}}}

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公开/公告号US2020054045A1

专利类型
公开/公告日2020-02-20

原文格式PDF
申请/专利权人 BIOMECHANICAL TECHNOLOGIES LLC;
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申请/专利号US201916665954
发明设计人 MICHAEL JAMES SCHMIDT;DAVID AVARBOCK;
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申请日2019-10-28
分类号A23L2/395;A23L2/66;A23L33/155;A23L33/195;A23L33/19;A23L33/185;A23L33/26;A23L33;A23L33/125;
国家 US
入库时间 2022-08-21 11:23:16

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