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TARGETING OF ANAPLASTIC LYMPHOMA KINASE IN SQUAMOUS CELL CARCINOMA
TARGETING OF ANAPLASTIC LYMPHOMA KINASE IN SQUAMOUS CELL CARCINOMA
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机译:鳞状细胞癌中非淋巴淋巴激酶的定位
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摘要
Methods for identifying patients with high risk (progression, invasion, metastasis) squamous cell carcinoma using methylation and/or expression assays are disclosed. Also provided are methods of treating such high risk cancers with ALK inhibitors combined with anti-EGFR based therapies, as the data show a correlation between ALK hypomethylation and EGFR activation.
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