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DISCOVERY AND VALIDATION OF AN EARLY POST-TRANSPLANT BIOMARKER PREDICTIVE OF CHRONIC KIDNEY DISEASE IN LIVER TRANSPLANT RECIPIENTS
DISCOVERY AND VALIDATION OF AN EARLY POST-TRANSPLANT BIOMARKER PREDICTIVE OF CHRONIC KIDNEY DISEASE IN LIVER TRANSPLANT RECIPIENTS
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机译:肝移植患者慢性肾脏病早期移植后生物标志物预测的发现和验证
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摘要
Disclosed are methods for predicting, inhibiting, and treating chronic kidney disease (CKD) in a subject that that is preparing to undergo a liver transplant. The methods may include detecting a protein biomarker in a serum sample from the subject prior to the subject being administered a liver transplant procedure and/or after the subject has been administered the liver transplant procedure. Suitable protein markers for the disclosed methods may include but are not limited to osteopontin (OPN) and/or tissue inhibitor of metalloproteases 1 (TIMP1).
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