Bottleneck bandwidth and round-trip propagation time (BBR) congestion control with random early detection (RED)

• 1. 一种强化学习与BBR算法结合的自适应拥塞控制方法及系统 [P] . 中国专利： CN113645144A . 2021-11-12
• 2. 一种基于BBR的拥塞控制方法、装置、设备和存储介质 [P] . 中国专利： CN110365600A . 2019-10-22
• 3. Bottleneck bandwidth and round-trip propagation time (bbr) congestion control with random early detection (red) [P] . 英国专利： GB202006912D0 . 2020.06.24
• 4. BOTTLENECK BANDWIDTH AND ROUND-TRIP PROPAGATION TIME (BBR) CONGESTION CONTROL WITH RANDOM EARLY DETECTION (RED) [P] . 世界知识产权组织专利： WO2019094211A1 . 2019-05-16

  机译： 随机早期检测的BOTTENECK带宽和圆带传播时间（BBR）拥塞控制

• 5. BOTTLENECK BANDWIDTH AND ROUND-TRIP PROPAGATION TIME (BBR) CONGESTION CONTROL WITH RANDOM EARLY DETECTION (RED) [P] . 美国专利： US2019140952A1 . 2019-05-09

  机译： 随机早期检测的BOTTENECK带宽和圆带传播时间（BBR）拥塞控制

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• 3. BBR Congestion-Based Congestion Control: MEASURING BOTTLENECK BANDWIDTH AND ROUND-TRIP PROPAGATION TIME [J] . NEAL CARDWELL, YUCHUNG CHENG, C. STEPHEN GUNN, ACM Queue: Architecting Tomorrow s Computing . 2016,第5期
• 4. Measuring bottleneck bandwidth and round-trip propagation time [J] . NEAL CARDWELL, YUCHUNG CHENG, C . STEPHEN GUNN, ACM Queue: Architecting Tomorrow s Computing . 2016,第5期
• 5. BBR-Based Congestion Control and Packet Scheduling for Bottleneck Fairness Considered Multipath TCP in Heterogeneous Wireless Networks [J] . Wei Wenjia, Xue Kaiping, Han Jiangping, IEEE Transactions on Vehicular Technology . 2021,第1期
• 6. BANDWIDTH AND ROUND-TRIP TIME DETECTION BASED CONGESTION CONTROL FOR MULTIPATH TCP OVER HIGHLY LOSSY SATELLITE NETWORKS [C] . Hefei Hu, Heng Li, Yuanan Liu IEEE Global Conference on Signal and Information Processing . 2019
• 7. TCP -- Random Early Detection (RED) mechanism for Congestion Control. [D] . Sungur, Asli. 2015
• 8. Improvement of RTT Fairness Problem in BBR Congestion Control Algorithm by Gamma Correction [O] . Wansu Pan, Xiaofeng Li, Haibo Tan, 2021
• 9. MULTIMEDIA STREAMING PLATFORM BANDWITH CONTROLL CONGESTION DETECTION AND BANDWIDTH ADAPTATION [O] . Ovidiu Răţoi, Haller Piroska 100

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. The Changes in the Neck Meridian Test Scores Induced by Self-Administered Acupressure: A Secondary Analysis of Data from a Randomized Controlled Trial of Self-Administered Acupressure [J] . Satoshi Horiuchi ,Yasuhiro Honda . 中医（英文） . 2017,第1期
• 3. New botanical drug, HL tablet, reduces hepatic fat as measured by magnetic resonance spectroscopy in patients with nonalcoholic fatty liver disease: A placebo-controlled, randomized, phase Ⅱ trial [J] . Jae Yoon Jeong ,Joo Hyun Sohn ,Yang Hyun Baek . 世界胃肠病学杂志：英文版 . 2017,第32期
• 4. 基于NS2软件验证随机早期检测算法RED的优越性 [C] . 孙栋栋 ,王玉斌 ,马争先 . 广西计算机学会2010年年会 . 2010
• 5. 多瓶颈网络拥塞控制若干问题研究 [A] . 侯辉 . 2009