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TREATMENT OF CYTOKINE RELEASE SYNDROME BY DECREASING LEVEL OF PROINFLAMMATORY CYTOKINE
TREATMENT OF CYTOKINE RELEASE SYNDROME BY DECREASING LEVEL OF PROINFLAMMATORY CYTOKINE
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机译：降低炎性细胞因子水平治疗细胞因子释放综合征
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摘要
The present invention provides a new method for decreasing level of a proinflammatory cytokine in a subject, which is further able to treating cytokine release syndrome caused by CAR T-cell therapy or a disorder mediated by an overproduction of a proinflammatory cytokine. The method comprises administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition which is comprising at least one selected from the group consisting of Phenothiazine derivatives, Graptopetalum paraguayense extract, Rhodiola rosea extract and Histone Deacetylase (HDAC) inhibitors.
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