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Biodynamic microscopes and methods of use thereof

机译:生物动力显微镜及其使用方法

摘要

An apparatus for viewing a biological sample that functions as both a microscope and an interferometer. A short-coherence light source directs light onto the sample. A Fourier transform lens and a pixel-array detector are positioned to collect light scattered by the sample. An optic fiber assembly conveys a reference beam from the short-coherence light source. The detector collects the reference beam and the signal beam and uses coherence gating to acquire interferometric image data. In some embodiments the axis of the incident light striking the sample and the axis of collected scattered signal light form an angle of less than 180 degrees and advantageously an angle between 120 and 150 degrees. A method of converting a microscope into an interferometer is also disclosed.
机译:一种用于观察生物样品的装置,其既用作显微镜又用作干涉仪。短相干光源将光引导到样品上。放置傅立叶变换透镜和像素阵列检测器以收集样本散射的光。光纤组件传输来自短相干光源的参考光束。检测器收集参考光束和信号光束,并使用相干门控来获取干涉图像数据。在一些实施例中,入射到样本的入射光的轴线和收集的散射信号光的轴线形成小于180度的角度,并且有利地在120度至150度之间的角度。还公开了一种将显微镜转换成干涉仪的方法。

著录项

  • 公开/公告号US10642014B2

    专利类型

  • 公开/公告日2020-05-05

    原文格式PDF

  • 申请/专利权人 PURDUE RESEARCH FOUNDATION;

    申请/专利号US201615068275

  • 发明设计人 DAVID D. NOLTE;JOHN J. TUREK;RAN AN;

    申请日2016-03-11

  • 分类号G02B21;G02B21/36;G02B21/08;G02B21/14;G02B21/24;G03H1;G02F1/21;G03H1/04;G02B6/28;F21V8;

  • 国家 US

  • 入库时间 2022-08-21 11:26:52

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