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Generation of heavy-chain only antibodies in transgenic animals
Generation of heavy-chain only antibodies in transgenic animals
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机译:在转基因动物中仅重链抗体的产生
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摘要
The present invention relates to a method for the generation of VH heavy chain-only antibodies in a transgenic non-human mammal. In particular, the present invention relates to a method for the production of a VH heavy chain-only antibody in a transgenic non-human mammal comprising the step of expressing more than one heterologous VH heavy chain locus in that mammal.
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机译:本发明涉及在转基因非人哺乳动物中产生仅V H Sub>重链抗体的方法。特别地,本发明涉及在转基因非人哺乳动物中产生仅V H Sub>重链抗体的方法,该方法包括表达多个异源V H的步骤。 Sub>该哺乳动物的重链基因座。
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