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Method to manufacture thin strut stent from bioabsorbable polymer with high fatigue and radial strength

机译:由具有高疲劳强度和径向强度的生物可吸收聚合物制造薄支柱支架的方法

摘要

The invention discloses a process for the preparation of a biodegradable stent which involves deforming an extruded biodegradable polymer tube axially at a first predefined temperature by applying an axial force for a first predefined time interval. The process is followed by radially expanding the axially stretched tube at a second predefined temperature by pressurizing the tube with an inert gas in one or more stages, the pressure applied in each successive stage being higher than the pressure applied in a previous stage. The process further comprises laser cutting a specific pattern of scaffold structure on the expanded tube and then crimping the laser cut stent on the balloon of delivery catheter in a sterile environment in multiple stages.
机译:本发明公开了一种制备生物可降解支架的方法,该方法包括通过在第一预定时间间隔内施加轴向力在第一预定温度下使挤出的生物可降解聚合物管轴向变形。在该过程之后,通过在一个或多个阶段中用惰性气体对管子进行加压,在第二预定温度下使轴向拉伸的管子径向膨胀,在每个连续阶段中施加的压力高于在先前阶段中施加的压力。该方法进一步包括在无菌环境中分多个阶段在扩张管上激光切割支架结构的特定图案,然后在递送导管的球囊上卷曲激光切割支架。

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