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Method of preparing biogenic silver nanoparticles

机译:生物银纳米粒子的制备方法

摘要

The method of preparing biogenic silver nanoparticles includes preparing an aqueous plant extract by boiling cut leaves of Alternanthera bettzickiana (Regel) G. Nicholson in distilled water, retaining the aqueous extract. The aqueous plant extracts were mixed with aqueous solutions of silver ions derived from different silver salt precursors (e.g., silver nitrate, silver sulfate, etc.). The resulting biogenic silver nanoparticles exhibit antimicrobial activity against various strains of gram-positive and gram-negative organisms, including some strains of drug-resistant microorganisms. The biogenic silver nanoparticles also exhibit anticancer activity against certain human cancer cell lines. Surprisingly, biogenic silver nanoparticles prepared from nitrate precursor exhibited greater anticancer activity than nanoparticles from sulfate precursor, while biogenic silver nanoparticles prepared from sulfate precursor exhibited greater antibacterial activity than nanoparticles from nitrate precursor.
机译:制备生物银纳米颗粒的方法包括通过在蒸馏水中煮沸切花白桦叶(Regel)G. Nicholson的切叶来制备水性植物提取物,并保留水性提取物。将植物水提取物与衍生自不同银盐前体(例如硝酸银,硫酸银等)的银离子水溶液混合。所得的生物银纳米颗粒显示出对各种革兰氏阳性和革兰氏阴性生物菌株,包括某些耐药微生物菌株的抗菌活性。生物银纳米颗粒还表现出对某些人类癌细胞系的抗癌活性。令人惊讶地,由硝酸盐前体制备的生物银纳米颗粒显示出比来自硫酸盐前体的纳米颗粒更大的抗癌活性,而由硫酸盐前体制备的生物银纳米颗粒显示出比来自硝酸盐前体的纳米颗粒更大的抗菌活性。

著录项

  • 公开/公告号US10828328B1

    专利类型

  • 公开/公告日2020-11-10

    原文格式PDF

  • 申请/专利权人 KING SAUD UNIVERSITY;

    申请/专利号US202016734152

  • 发明设计人 R. JOTHI RAMALINGAM;HAMAD AL LOHEDAN;

    申请日2020-01-03

  • 分类号A61K33/38;A61K36/21;B82Y40;B82Y5;

  • 国家 US

  • 入库时间 2022-08-21 11:28:27

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