首页> 外国专利> Quantification of inflammatory molecules in exhaled breath condensate using differential pulse voltammetry on reduced graphene oxide sensor

Quantification of inflammatory molecules in exhaled breath condensate using differential pulse voltammetry on reduced graphene oxide sensor

机译：在还原的氧化石墨烯传感器上使用差分脉冲伏安法对呼出气冷凝物中的炎症分子进行定量

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摘要

A device for detecting a biomarker for inflammation in a respiratory system includes a sample collection and/or holding area to receive an exhaled breath condensate (EBC) sample obtained from a respiratory system; an electrode system coupled to the sample collection area, the electrode system including reduced graphene oxide (rGO); and circuitry coupled to the electrode system. The circuitry is configured to apply a voltage to the EBC sample in the sample collection area via the electrode system and to measure a current via the electrode system in response to the voltage applied, in order to determine a concentration of nitrite in the EBC sample based on the current measured. The concentration of nitrite is a biomarker for inflammation in the respiratory system.

机译：一种用于检测呼吸系统中炎症的生物标志物的设备，包括样品收集和/或保持区域，以接收从呼吸系统获得的呼出气冷凝物（EBC）样品;电极系统耦合到样品收集区域，该电极系统包括还原的氧化石墨烯（rGO）;和耦合到电极系统的电路。该电路被配置为通过电极系统向样品收集区域中的EBC样品施加电压，并响应于所施加的电压通过电极系统测量电流，从而确定基于EBC样品中亚硝酸盐的浓度。在测量的电流上。亚硝酸盐的浓度是呼吸系统炎症的生物标记。

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公开/公告号US10670580B2

专利类型
公开/公告日2020-06-02

原文格式PDF
申请/专利权人 RUTGERS THE STATE UNIVERSITY OF NEW JERSEY;
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申请/专利号US201815997598
发明设计人 MEHDI JAVANMARD;AZAM GHOLIZADEH;MANISH CHHOWALLA;ROBERT J. LAUMBACH;HOWARD M. KIPEN;CLIFFORD P. WEISEL;ANDREW J. GOW;DAMIEN VOIRY;
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申请日2018-06-04
分类号G01N33/497;H01M8;A61B5/08;A61B5/097;A61M16/08;G01N27/48;A61B5;
国家 US
入库时间 2022-08-21 11:28:29

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