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Method for predicting risk of exposure to interstitial fibrosis and tubular atrophy with clusterin

机译:簇蛋白预测间质纤维化和肾小管萎缩风险的方法

摘要

A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
机译:一种用于鉴定处于发生间质纤维化或肾小管萎缩的风险增加的肾移植受者的方法,该方法包括从肾移植受者获得移植后的尿液样品;测量尿液样本中的簇蛋白水平;比较来自非纤维化肾脏移植接受者尿液中患者样品中的簇蛋白水平与对照样品中的簇蛋白水平;诊断肾移植受者的簇蛋白水平明显高于对照组中的簇蛋白水平,因为其发生间质性纤维化或肾小管萎缩的风险增加。

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