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Biomarkers for risk assessment and treatment monitoring in heart failure patients guided by natriuretic peptides

机译：心钠素肽指导心力衰竭患者的风险评估和治疗监测生物标志物

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摘要

The present description relates to a method for identifying a patient who is eligible for an intensification of heart failure therapy. Furthermore, the description relates to a method for optimizing B type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy. The methods are based on the measurement of the level of at least one marker in a sample from a patient who has heart failure and who receives B-type natriuretic peptide (BNP) and/or N-terminal pro B-type natriuretic peptide (NT-proBNP)-type peptide guided heart failure therapy. Further described are kits and devices adapted to carry out the described method.

机译：本说明书涉及一种用于识别有资格进行强化心力衰竭治疗的患者的方法。此外，该描述涉及用于优化B型利钠肽（BNP）和/或N端前B型利尿肽（NT-proBNP）型肽引导的心力衰竭治疗的方法。该方法基于对患有心力衰竭并且接受B型利钠肽（BNP）和/或N端B型利尿钠肽（NT）的患者的样品中至少一种标记物的测量-proBNP）型肽指导的心力衰竭治疗。进一步描述了适于执行所述方法的试剂盒和装置。

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公开/公告号US10684291B2

专利类型
公开/公告日2020-06-16

原文格式PDF
申请/专利权人 ROCHE DIAGNOSTICS OPERATIONS INC.;
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申请/专利号US201615220555
发明设计人 DIRK BLOCK;HANS-PETER BRUNNER;URSULA-HENRIKE WIENHUES-THELEN;CHRISTIAN ZAUGG;THOMAS DIETERLE;CHERYL MITCHELL;JOHAN UBBY;SANDRA SANDERS-VAN WIJK;
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申请日2016-07-27
分类号G01N33/53;G01N33/68;G01N33/62;G01N33/66;G01N33/70;G01N33/72;G01N33/84;
国家 US
入库时间 2022-08-21 11:31:35

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