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Colorectal cancer model animal, method for producing colorectal cancer model animal, anticancer agent, allergy model animal, method for producing allergy model animal, and screening method
Colorectal cancer model animal, method for producing colorectal cancer model animal, anticancer agent, allergy model animal, method for producing allergy model animal, and screening method
PROBLEM TO BE SOLVED: To provide a colon cancer model animal, a production method of the colon cancer model animal, an allergy model animal, a production method of the allergy model animal, and a screening method using the model animal.SOLUTION: A colon cancer model animal being a non-human animal is provided in which the function of the Gsdmd gene is missed or deteriorated. An allergy model animal being the non-human animal is provided in which the function of the Gsdmd gene is missed or deteriorated, and an allergic disease is easy to be developed. A production method of the model animal comprises a step of administering a colon cancer-specific carcinogen and a colon respiratory substance to the non-human animal in which the function of the Gsdmd gene is missed or deteriorated.SELECTED DRAWING: None
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