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METHODS FOR THE PROGNOSIS OF HIV-INFECTED SUBJECTS

机译：艾滋病毒感染者的预后方法

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摘要

The invention provides an in vitro method, kits, uses of said kits and of reagents, for determining the prognosis of an HIV-infected subject having an undetectable viral load in the absence of antiretroviral treatment (or of an Ellite Controler HIV-infected subject) by determining the expression level of at least one biomarker selected from the group consisting of Galectin-3-binding protein (LG3BP), α-1-antichymotrypsin (AACT), Ficolin-2 (FCN2), 14-3-3 protein zeta/delta (1433Z) and coagulation factor XI (FA11) in a sample from said subject, and comparing the expression level of said at least one biomarker with a reference value.

机译：本发明提供了一种体外方法，试剂盒，所述试剂盒和试剂的用途，用于确定在没有抗逆转录病毒治疗（或未检测到HIV）的情况下具有不可检测的病毒载量的HIV感染的受试者的预后。 Ellite Controler HIV感染者），通过确定至少一种生物标志物的表达水平，所述生物标志物选自Galectin-3结合蛋白（LG3BP），α-1-抗胰凝乳蛋白酶（AACT），Ficolin-2（FCN2），14将来自所述受试者的样品中的-3-3蛋白ζ/δ（1433Z）和凝血因子XI（FA11），并将所述至少一种生物标志物的表达水平与参考值进行比较。 展开▼

著录项

公开/公告号EP3623813A1

专利类型

公开/公告日2020-03-18

原文格式PDF

申请/专利权人 INSTITUT DINVESTIGACIÓ SANITÀRIA PERE VIRGILI;UNIVERSITAT ROVIRA I VIRGILI;SERVICIO ANDALUZ DE SALUD;
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申请/专利号EP20180382669

发明设计人 RODRÍGUEZ GALLEGO ESTHER;RULL AIXA ANNA;VIDAL MARSAL FRANCESC;ALBA ELVIRA VERÓNICA;RUIZ-MATEOS CARMONA EZEQUIEL;LÓPEZ CORTÉS LUIS FERNANDO;TARANCÓN DÍEZ LAURA;PERAIRE FORNER JOAQUIM;VILADÉS LABORDA CONSUELO;
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申请日2018-09-17

分类号G01N33/569;

国家 EP

入库时间 2022-08-21 11:39:33

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2. 疾病预后模型的制作方法、使用该模型的疾病预后预测方法、利用该模型的预后预测装置以及其程序·存储介质 [P] . 中国专利： CN1777806A . 2006-05-24

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机译：艾滋病毒感染者的预后方法

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机译：确定来自用生物药物治疗的受试者的生物样品中中和抗药物抗体（游泳）水平的方法，评估受试者对使用生物药物治疗的反应性，监测疾病进展和早期预后的预后方法疾病复发，用于检测用所述生物药物治疗的受试者的生物样品中的任何东西的装置，试剂盒，用于确定用所述疾病生物药物治疗的受试者的生物样品中活性生物药物水平的方法

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