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SMALL-MOLECULE POLYPEPTIDE ZY4 AND APPLICATION THEREOF

机译：小分子多肽ZY4及其应用

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摘要

The present invention discloses the use of low molecular polypeptide ZY4 in preparing drugs for acne, infection and cancer as well as cosmetics. It comprises 17 amino acid residues, with a molecular weight of 2374.0 Da, an isoelectric point of 10.74, and its amino acid sequence is as shown in SEQ ID:1. The low molecular polypeptide ZY4 in the invention is artificially synthesized, with the advantages of small molecular weight and convenient artificial synthesis. The experiments have showed that the polypeptide ZY4 has clear antibacterial effect and has significant therapeutic effect on acne. The polypeptides can inhibit the growth of tumor cells and kill tumor cells; and the low molecular polypeptide ZY4 can be used in the preparation of anti-infective, anti-tumor and anti-acne medicaments and cosmetics.

机译：本发明公开了低分子多肽ZY4在制备用于痤疮，感染和癌症的药物以及化妆品中的用途。它包含17个氨基酸残基，分子量为2374.0Da，等电点为10.74，并且其氨基酸序列如SEQ ID：1所示。本发明的低分子多肽ZY4是人工合成的，具有分子量小，人工合成方便的优点。实验表明，多肽ZY4具有明显的抗菌作用，对痤疮具有显着的治疗作用。这些多肽可以抑制肿瘤细胞的生长并杀死肿瘤细胞。低分子多肽ZY4可用于制备抗感染，抗肿瘤，抗粉刺的药物和化妆品。

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公开/公告号EP3309167B1

专利类型
公开/公告日2019-11-27

原文格式PDF
申请/专利权人 SICHUAN HETAI SYNLIGHT BIOTECH LTD.;KUNMING INSTITUTE OF ZOOLOGY THE CHINESE ACADEMY OF SCIENCES;
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申请/专利号EP20160810713
发明设计人 LAI REN;RONG MINGQIANG;DU YANJUN;
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申请日2016-01-12
分类号C07K7/08;A61P31/04;A61P17/10;A61P35;
国家 EP
入库时间 2022-08-21 11:40:17

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