首页> 外国专利> CHALLENGE TEST FOR DIAGNOSING A SUBTYPE OF AUTISM SPECTRUM DISEASE

CHALLENGE TEST FOR DIAGNOSING A SUBTYPE OF AUTISM SPECTRUM DISEASE

机译:诊断自闭症谱系疾病亚型的挑战性试验

摘要

The present invention is directed to a method of identifying autism spectrum disorder (ASD) subtype 1 patients, wherein the method comprises: administering an Nrf2-activator to an ASD patient previously diagnosed with ASD or a subject displaying clinical signs of ASD, and identifying the ASD patient as an ASD subtype 1 patient if the patient shows a negative response after administration of the Nrf2-activator. Likewise, the present invention is directed to an Nrf2-activator for use in identifying autism spectrum disorder (ASD) subtype 1 patients, wherein the Nrf2-activator is administered to a subject, wherein the subject is a patient previously diagnosed with ASD or a subject displaying clinical signs of ASD and wherein an ASD subtype 1 patient is identified by a negative response.
机译:本发明涉及一种鉴定自闭症谱系障碍(ASD)亚型1患者的方法,其中该方法包括:向先前诊断出患有ASD的ASD患者或表现出ASD临床症状的受试者施用Nrf2激活剂,并鉴定如果该患者在服用Nrf2激活剂后显示阴性反应,则为ASD 1型患者。同样,本发明涉及用于鉴定自闭症谱系障碍(ASD)亚型1患者的Nrf2激活剂,其中所述Nrf2激活剂被施用于受试者,其中所述受试者是先前被诊断出患有ASD的患者或受试者。显示ASD的临床体征,并且其中ASD 1型亚型患者通过阴性反应来识别。

著录项

  • 公开/公告号EP3706806A1

    专利类型

  • 公开/公告日2020-09-16

    原文格式PDF

  • 申请/专利权人 STALICLA S.A.;

    申请/专利号EP20180795688

  • 发明设计人 DURHAM LYNN;

    申请日2018-11-06

  • 分类号A61K49;

  • 国家 EP

  • 入库时间 2022-08-21 11:41:09

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