首页> 外国专利> METHOD FOR PREDICTION OF SEVERITY OF ISCHEMIC PROCESS OF HEART, CEREBRUM AND LOWER LIMBS BASED ON ASSESSMENT OF CENTRAL AND REGIONAL HAEMODYNAMICS OF ORGANS

METHOD FOR PREDICTION OF SEVERITY OF ISCHEMIC PROCESS OF HEART, CEREBRUM AND LOWER LIMBS BASED ON ASSESSMENT OF CENTRAL AND REGIONAL HAEMODYNAMICS OF ORGANS

机译:基于器官中部和区域血流动力学评估的心,脑和下肢缺血过程严重程度的预测方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to prediction of severity of ischemic process of heart, brain and lower limbs based on assessment of central and regional haemodynamics of organs. What is presented is a method which involves measuring systolic blood pressure at a given time (SBP), heart rate (HR), a difference in systolic and arterial pressure and three days ago (ΔAP), activated partial thromboplastin time (APTT) and concentration of Ca2+ in blood [Ca2+]. Self-regulation criterion of central hemodynamic system Z is determined by formula ; , ;wherein parameter Z is used as a basic variable, on which membership functions are determined μr(Z), determining confidence in classification of severity of ischemic process of central hemodynamic system, wherein four classes are distinguished, characterizing severity r: r = n - norm; r = l is a latent state; r = p is a reversible state; r = c is a critical condition, the patient refers to that class of severity of ischemic process of central hemodynamic system, function of belonging of which is maximum, by value Z is determined function of severity of ischemic process of central hemodynamic system fz(Z), integral levels of severity of ischemic process in heart Uh, brain Ub and lower extremities Ue, by which, taking into account the state of central hemodynamic system, severity of ischemic process for heart STh, for brain STb and lower extremities STe are determined by expressions: STh = fZ(Z) + Uh∙[1-fZ(Z)], STb = fZ(Z) + Ub∙[1-fZ(Z)], STe = fZ(Z) + Ue∙[1-fZ(Z)], on scales STh, STb and STe functions of belonging to the same gravity classes are determined, as for central hemodynamic system - for heart μr(STh), for cerebrum μr(STb), for lower extremities μr(STe), r = n, l, p, c, and for each organ severity is determined by maximum value of corresponding membership functions.;EFFECT: invention provides higher quality of prediction of degree of severity of central hemodynamic system, ischemic process of heart, cerebrum and lower extremities.;10 cl, 4 tbl, 3 ex, 15 dwg
机译:发明领域本发明涉及基于对器官的中央和区域血流动力学的评估来预测心脏,大脑和下肢缺血过程的严重性。提出了一种涉及在给定时间测量收缩压(SBP),心率(HR),三天前收缩压和动脉压的差异(ΔAP),活化的部分凝血活酶时间(APTT)和浓度的方法血[Ca 2 + ]中Ca 2 + 的含量。中央血流动力学系统Z的自我调节标准由公式确定; ,其中参数Z用作基本变量,在该变量上确定隶属函数μ r (Z),确定对中央血液动力学系统缺血过程严重程度分类的置信度,其中区分了四个类别,表征严重程度r:r = n-规范; r = l为潜伏状态; r = p是可逆状态; r = c为临界状态,患者指的是中央血液动力学系统缺血过程严重程度的类别,其归属功能最大,通过值Z确定中央血液动力学系统缺血过程严重程度的函数f z (Z),心脏U h ,脑U b 和下肢U e ,考虑到中央血液动力学系统的状态,心脏ST h ,脑ST b 和下肢ST e缺血过程的严重程度由以下表达式确定:ST h = f Z (Z)+ U h ∙[1-f Z (Z)],ST b = f Z (Z)+ U b ∙[1-f Z (Z)],ST e = f Z (Z)+ U e ∙[1-f Z (Z)],确定属于相同引力类别的尺度ST h ,ST b 和ST e ,关于中央血流动力学c系统-心脏μ r (ST h ),大脑μ r (ST b ),下肢μ r (ST e ),r = n,l,p,c,对于每种器官,其严重程度取决于相应隶属函数的最大值。 :本发明提供了对中心血液动力学系统的严重程度,心脏,大脑和下肢的缺血过程的严重程度的预测的高质量。; 10 cl,4 tbl,3 ex,15 dwg

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