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USING PHARMACEUTICAL COMPOSITION FOR TREATING OR CREATING REMISSION CONDITIONS IN ELDERLY PATIENT WITH SOLID CANCER
USING PHARMACEUTICAL COMPOSITION FOR TREATING OR CREATING REMISSION CONDITIONS IN ELDERLY PATIENT WITH SOLID CANCER
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机译：使用药物组合物治疗或降低患有固体癌症的老年患者的缓解情况
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摘要
FIELD: medicine; biotechnology.;SUBSTANCE: group of inventions relates to biotechnology and medicine, in particular to use of a pharmaceutical composition for treating an elderly human patient with solid cancer or a human patient at the terminal stage of solid cancer or to create remission conditions in an elderly human patient with solid cancer or in a human patient at the terminal stage of solid cancer. Composition contains as active ingredient 10 mg (2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoylamino]-4-methylpentanoic acid or its pharmacologically acceptable salt. Composition is administered to the patient once a day. Said elderly human patient represents person of 70 years or older and has a neutrophil count to lymphocyte count in peripheral blood 4 or higher and/or has a ratio of thrombocyte count to lymphocyte count in peripheral blood 1.5 or higher. Also disclosed are a combination drug and a kit containing said pharmaceutical composition and an anticancer agent and/or a molecular-targeted drug.;EFFECT: invention enables treating elderly patients with solid cancer and patients at the terminal stage of solid cancer with fewer side effects in order to improve and maintain quality of life and prolong life.;5 cl, 20 dwg, 5 tbl, 15 ex
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机译：领域：医学;生物技术;发明组：生物技术和医学，特别是涉及药物组合物在治疗患有实体癌的老年人患者或处于实体癌末期的人类患者或在老年人中创造缓解条件的用途患有实体癌的人类患者或处于实体癌末期的人类患者。组合物含有10mg（2S）-2-[（2S，3R）-3-氨基-2-羟基-4-苯基丁酰基氨基] -4-甲基戊酸或其药理学上可接受的盐作为活性成分。每天一次向患者施用组合物。所述老年患者代表70岁或以上的人，并且外周血中嗜中性粒细胞计数与淋巴细胞计数为4或更高，和/或外周血中血小板计数与淋巴细胞计数之比为1.5或更高。还公开了组合药物和包含所述药物组合物以及抗癌剂和/或分子靶向药物的试剂盒。效果：本发明使得能够治疗老年实体瘤患者和实体癌晚期患者的副作用更少为了改善和维持生活质量并延长寿命。; 5 cl，20 dwg，5 tbl，15 ex
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