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METHOD FOR PREDICTING PRETERM LABOR BY JOINTLY DETERMINING EXTRACELLULAR DNA AND NEUTROPHIL-ACTIVATING FACTOR IN PERIPHERAL BLOOD PLASMA

机译：联合测定外周血血浆胞外DNA和中性激活因子预测早产的方法

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摘要

FIELD: medicine.;SUBSTANCE: invention relates to the field of medicine, in particular to obstetrics, and is intended to predict preterm labor. Using indicators of the concentration of the total amount of extracellular DNA (ovDNA) and the concentration of IL-8 in peripheral blood plasma in pregnant women at 22-36 weeks of gestation, the variable P is determined. At P 0.5, preterm labor will occur. When P ≤ 0.5, preterm labor will not occur.;EFFECT: invention provides an effective prediction of preterm labor by the joint determination of ovDNA and neutrophil-activating factor in peripheral blood plasma.;1 cl, 1 dwg, 3 ex

机译：技术领域本发明涉及医学领域，特别是涉及产科，并用于预测早产。使用妊娠22-36周时孕妇的细胞外DNA（ovDNA）总量浓度和外周血浆IL-8浓度的指标，确定变量P。在P> 0.5时会发生早产。当P≤0.5时，不会发生早产。效果：本发明通过联合测定外周血浆中的ovDNA和嗜中性粒细胞活化因子提供了对早产的有效预测。1cl，1 dwg，3 ex

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公开/公告号RU2682713C1

专利类型
公开/公告日2019-03-21

原文格式PDF
申请/专利权人 FEDERALNOE GOSUDARSTVENNOE BYUDZHETNOE UCHREZHDENIE NATSIONALNYJ MEDITSINSKIJ ISSLEDOVATELSKIJ TSENTR AKUSHERSTVA GINEKOLOGII I PERINATOLOGII IMENI AKADEMIKA V.I. KULAKOVA MINISTERSTVA ZDRAVOOKHRANENIYA ROSSIJSKOJ FEDERATSII;
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申请/专利号RU20180108827
发明设计人 MEDZHIDOVA MARZHANAT KAPUROVNA (RU);TYUTYUNNIK VIKTOR LEONIDOVICH (RU);SALPAGAROVA ZALINA KHUSEEVNA (RU);SADEKOVA ALSU AMIROVNA (RU);SARIBEKOVA ALENA GARRIEVNA (RU);KOKOEVA DIANA NIKOLAEVNA (RU);KRASNYJ ALEKSEJ MIKHAJLOVICH (RU);KAN NATALYA ENKYNOVNA (RU);
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申请日2018-03-13
分类号G01N33/50;C12Q1/68;
国家 RU
入库时间 2022-08-21 11:46:19

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