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USE OF OPIOID RECEPTOR ANTAGONIST WITH K-ACTIVITY AND VORTIOXETINE FOR TREATMENT OF DEPRESSIVE DISORDER WITH MELANCHOLIC FEATURES
USE OF OPIOID RECEPTOR ANTAGONIST WITH K-ACTIVITY AND VORTIOXETINE FOR TREATMENT OF DEPRESSIVE DISORDER WITH MELANCHOLIC FEATURES
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机译:具有K活性和伏立西汀的阿片受体拮抗剂在治疗忧郁性抑郁症中的应用
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摘要
FIELD: medicine.;SUBSTANCE: disclosed is a pharmaceutical composition for the treatment of depressive disorder with melancholic features, comprising an opioid antagonist with κ-activity where said opioid antagonist with κ-activity is nalmefene or a pharmaceutically acceptable salt thereof, and vortioxetine or a pharmaceutically acceptable salt thereof, together with a pharmaceutically acceptable excipient.;EFFECT: technical result: high efficiency compared with use of nalmefene or vortioxetine separately.;1 cl, 2 dwg, 1 tbl, 3 ex
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机译:领域:公开了一种用于治疗具有忧郁特征的抑郁症的药物组合物,其包含具有κ-活性的阿片样物质拮抗剂,其中所述具有κ-活性的阿片样物质拮抗剂是纳美芬或其药学上可接受的盐,以及伏替西汀或效果:技术成果:与纳美芬或伏地西汀分别使用相比,效率更高; 1 cl,2 dwg,1 tbl,3 ex
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