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METHOD FOR SELECTING AN APPROACH FOR TREATING AGGRESSIVE POSTERIOR RETINOPATHY OF PREMATURITY AT DISEASE ONSET

机译:疾病发作前的治疗性早发性骨性视网膜病变的治疗方法选择方法

摘要

FIELD: medicine.;SUBSTANCE: invention relates to medicine, namely to ophthalmology, and can be used to select an approach for treating aggressive posterior retinopathy of prematurity at disease onset. Diameter of central arteries and the coefficient of tortuosity of arteries are determined during the preoperative examination of a patient. Obtained values are substituted into the equation of logistic regression: Z=exp(55.2726+(-0.1584)*X+(-35.3911)*Y)/(1+exp(55.2726+(-0.1584)*X+(-35.3911)*Y)), wherein X is a diameter of central arteries of the patient, Y is a coefficient of tortuosity of arteries of the patient. If Z0.5, the patient undergoes surgical treatment – primary vitrectomy. If Z0.5, the patient undergoes laser treatment – transpupillary retina laser coagulation (RLC). If Z=0.5, ophthalmic ultrasonography is performed, and when a retinal detachment is detected, the patient undergoes surgical treatment – primary vitrectomy. In the absence of retinal detachment, the patient undergoes laser treatment – transpupillary RLC.;EFFECT: method provides an informed choice of an effective method of treatment with the achievement of a stable regression of the disease in the postoperative period with a probability of 96 % due to the application of a diagnostic model based on logistic regression.;1 cl, 5 ex
机译:技术领域本发明涉及医学,即眼科,并且可以用于选择治疗疾病发作时的早产的侵袭性后视网膜病变的方法。在患者的术前检查期间确定中央动脉的直径和动脉曲折系数。将获得的值代入logistic回归方程:Z = exp(55.2726 +(-0.1584)* X +(-35.3911)* Y)/(1 + exp(55.2726 +(-0.1584)* X +(-35.3911)* Y )),其中X是患者中央动脉的直径,Y是患者动脉的曲折系数。如果Z <0.5,则患者接受手术治疗-原发玻璃体切除术。如果Z> 0.5,则患者接受激光治疗-经瞳孔视网膜激光凝结(RLC)。如果Z = 0.5,则进行眼科超声检查,并且当检测到视网膜脱离时,患者将接受手术治疗-原发性玻璃体切除术。在没有视网膜脱离的情况下,患者接受激光治疗-经瞳孔RLC .;效果:该方法提供了一种有效的治疗方法的知情选择,可在术后实现疾病的稳定消退,可能性为96%由于应用了基于Logistic回归的诊断模型。; 1 cl,5 ex

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