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首页> 外国专利> METHOD FOR DIFFERENTIAL DIAGNOSTICS OF VEGETATIVE CONDITION AND CONDITION OF MINIMAL CONSCIOUSNESS IN PATIENTS WITH CHRONIC DISORDERS OF CONSCIOUSNESS

METHOD FOR DIFFERENTIAL DIAGNOSTICS OF VEGETATIVE CONDITION AND CONDITION OF MINIMAL CONSCIOUSNESS IN PATIENTS WITH CHRONIC DISORDERS OF CONSCIOUSNESS

机译：慢性意识障碍患者的营养状况和最低意识状况的鉴别诊断方法

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FIELD: medicine.;SUBSTANCE: invention relates to the field of medicine, namely to neurology and radiation diagnosis, and can be used for the differential diagnosis of the vegetative state and the state of minimal consciousness in patients with chronic impairment of consciousness. MRI scans of the brain are performed in a spin echo sequence, producing T2-weighted images of the brain in the axial plane, and 3D gradient echo, producing T1 weighted images in the sagittal plane. Absence of general atrophy of the cortex, moderate and pronounced changes in internal and external hydrocephalus, leukoaraiosis, degeneration of the corpus callosum and foci in it and degeneration of the brainstem are estimated to be 0 points. General atrophy of the cortex, degeneration of the brainstem, foci in the corpus callosum, and moderate manifestations of internal hydrocephalus are estimated at 1 point, when the Evans index is 0.31–0.74, and external hydrocephalus – when the subarachnoid furrows expand to 0.4 cm, leukoaraiosis in the form of diffuse zones of altered intensity of the MR signal near the lateral ventricles and degeneration of the corpus callosum when the thickness of its middle sections is 0.2–0.4 cm. Presence of pronounced manifestations of internal hydrocephalus is estimated at 2 points when the Evans index is more than 0.74, external hydrocephalus – when the expansion of subarachnoid furrows over 0.4 cm, leukoaraiosis in the form of diffuse zones of altered intensity of the MR signal around the lateral ventricles, which merge into extensive zones, extending to the whole white matter up to the cortex and degeneration of the corpus callosum, when the thickness of its middle parts is less than 0.2 cm. Then, a total sum of points is calculated and if it equals 6 and more, a vegetative state is established; if it equals less than 6, a state of minimal consciousness is established.;EFFECT: method provides an increase in the reliability and accuracy of the differential diagnosis of the vegetative state and the state of minimal consciousness in patients with chronic impairment of consciousness due to the objectification of the detection of brain damage using MRI scans and calculation of the total sum of points of brain damage.;1 cl, 3 dwg, 1 tbl, 2 ex
机译：药物领域本发明涉及医学领域，即神经病学和放射诊断，可用于慢性意识障碍患者的营养状态和最低意识状态的鉴别诊断。以旋转回波序列执行大脑的MRI扫描，在轴向平面中生成大脑的T2加权图像，在3D梯度回波中，在矢状平面中生成T1加权图像。缺乏皮质的一般性萎缩，内部和外部脑积水的中度和明显变化，白质疏松症，call体及其中的病灶变性以及脑干变性估计为0分。当Evans指数为0.31-0.74时，皮质的一般萎缩，脑干退化，call体病灶和中度脑积水的表现估计为1点，而当蛛网膜下腔犁沟扩展至0.4 cm时，则为外部脑积水。 ，当其中间部分的厚度为0.2-0.4 cm时，白细胞软化症的形式为弥散区，其在侧脑室附近的MR信号强度发生了改变，并使call体退化。当Evans指数大于0.74时，内部脑积水的显着表现估计为2个点;外部脑积水–当蛛网膜下腔的皱纹扩张超过0.4 cm时，白斑病以弥散区的形式出现，MR信号强度改变。当其中间部分的厚度小于0.2 cm时，侧脑室合并成宽阔的区域，延伸至整个白质直至皮质和and体退化。然后，计算总点数，如果总和等于6或更大，则建立植物状态。如果其值小于6，则建立了最低意识状态。;效果：该方法提高了由于以下原因导致的慢性意识障碍患者的营养状态和最低意识状态的鉴别诊断的可靠性和准确性： MRI扫描检测脑损伤的目的并计算脑损伤总点数。1cl，3 dwg，1 tbl，2 ex

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