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PA14 Novel Imipenem Resistant Pseudomonas aeruginosa specific bacteriophage PA14 and antibacterial composition comprising the same
PA14 Novel Imipenem Resistant Pseudomonas aeruginosa specific bacteriophage PA14 and antibacterial composition comprising the same
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机译：PA14新型耐亚胺培南的铜绿假单胞菌特异性噬菌体PA14和包含其的抗菌组合物
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摘要
The present invention is a novel bacteriophage PA14 having a specific killing ability against antibiotic-resistant Pseudomonas aeruginosa, particularly Imipenem Resistant Pseudomonasaeruginosa (IRPA), an antibiotic composition comprising the bacteriophage, feed composition, feed, disinfectant or cleaning agent, and The present invention relates to a method for preventing or treating an infectious disease caused by imipenem-resistant Pseudomonas aeruginosa comprising administering the bacteriophage to an individual except a human. The method for preventing or treating an infectious disease caused by imipenem-resistant Pseudomonas aeruginosa using bacteriophage PA14 of the present invention has a higher specificity for Pseudomonas aeruginosa, particularly antibiotic-resistant Pseudomonas aeruginosa, and the bacteriophage PA14 infects Pseudomonas aeruginosa. By proliferating in Pseudomonas aeruginosa, lytic activity is excellent, and Pseudomonas aeruginosa killing ability is excellent. In addition, the bacteriophage PA14 of the present invention is not infected with other hosts other than bacteria such as humans, animals and plants, and thus has the advantage of solving the problems of antibiotic resistant bacteria due to the misuse of antibiotics, the residual problem of antibiotics in food, and the problem of a wide range of hosts. have. Therefore, the bacteriophage PA14 of the present invention can be used in various fields in the prevention or treatment of infectious diseases caused by imipenem-resistant Pseudomonas aeruginosa, antibiotic compositions, feed additive compositions, feed, disinfectants, or detergents.
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