首页>
外国专利>
TARGET MOLECULE TO WHICH AMYLOSPHEROID BINDS AND INDUCES MATURE NEURONAL CELL DEATH METHOD AND SUBSTANCE FOR INHIBITING AMYLOSPHEROID-INDUCED NEURONAL CELL DEATH AND USES FOR SAID TARGET MOLECULE METHOD AND SUBSTANCE
TARGET MOLECULE TO WHICH AMYLOSPHEROID BINDS AND INDUCES MATURE NEURONAL CELL DEATH METHOD AND SUBSTANCE FOR INHIBITING AMYLOSPHEROID-INDUCED NEURONAL CELL DEATH AND USES FOR SAID TARGET MOLECULE METHOD AND SUBSTANCE
In one or more embodiments, it is a target molecule of amylose pelloid that expresses in mature neurons, and binds to amylose ferroide to provide a target molecule that is induced by cell death. Also, in one or more embodiments, methods and materials are provided for inhibiting amylose ploid-induced mature neuronal cell death. In one aspect, the invention relates to the use of Na + / K + -ATPase alpha 3 as the binding target molecule of amylose ferroide. In another aspect, the present invention relates to a method for inhibiting amylose pheolide-induced mature neuronal cell death, which comprises inhibiting the interaction between amylose ferroide and Na + / K + -ATPase alpha 3 protein.
展开▼
机译：在一个或多个实施方案中，直链淀粉类固醇的靶分子在成熟神经元中表达，并结合直链淀粉铁化物以提供由细胞死亡诱导的靶分子。同样，在一个或多个实施方式中，提供了用于抑制直链淀粉样物诱导的成熟神经元细胞死亡的方法和材料。一方面，本发明涉及Na + / K + -ATPaseα3作为直链淀粉铁化物的结合靶分子的用途。在另一方面，本发明涉及一种抑制直链淀粉的乙醇化物诱导的成熟神经元细胞死亡的方法，其包括抑制直链淀粉的铁与Na + / K + 之间的相互作用。 -ATPase alpha 3蛋白。
展开▼
