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Early diagnostic biomarker for essential hypertension in Korean women

机译:韩国女性原发性高血压的早期诊断生物标志物

摘要

(SNP) located in the promoter region of the angiotensin converting enzyme (ACE) gene. The present invention also relates to a composition for diagnosing essential hypertension in a female female. More specifically, the present invention relates to a composition for the diagnosis of essential hypertension in Korean female, characterized by being rs4291, rs4292, and / or rs4363 among the angiotensin converting enzyme (ACE) gene related to the renin-angiotensin system, A diagnostic kit, and an information providing method for prediction. Ultimately, the present invention can provide diagnostic compositions, diagnostic kits, and information providing methods for predicting hypertension that enable early diagnosis of essential female hypertension in Korean, and can be used for early treatment of Korean female essential hypertension It is expected to be able to do.
机译:(SNP)位于血管紧张素转换酶(ACE)基因的启动子区域。本发明还涉及用于诊断女性雌性高血压的组合物。更具体地,本发明涉及用于诊断韩国女性原发性高血压的组合物,其特征在于与肾素-血管紧张素系统有关的血管紧张素转化酶(ACE)基因中的rs4291,rs4292和/或rs4363。套件,以及用于预测的信息提供方法。最终,本发明可以提供用于预测高血压的诊断组合物,诊断试剂盒和信息提供方法,所述诊断组合物,诊断试剂盒和提供信息的方法使得能够早期诊断韩国人的女性原发性高血压,并且可以用于韩国女性原发性高血压的早期治疗。做。

著录项

  • 公开/公告号KR101946645B1

    专利类型

  • 公开/公告日2019-02-11

    原文格式PDF

  • 申请/专利权人 가톨릭대학교 산학협력단;

    申请/专利号KR20120054805

  • 发明设计人 김성주;박종근;

    申请日2012-05-23

  • 分类号C12Q1/68;C12N15/11;

  • 国家 KR

  • 入库时间 2022-08-21 11:49:10

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