首页> 外国专利> 1 PHARMACEUTICAL COMPOSITION COMPRISING SILKWORM STORAGE PROTEIN 1 FOR PREVENTING OR TREATING ENDOPLASMIC RETICULUM STRESS-RELATED DISEASES

1 PHARMACEUTICAL COMPOSITION COMPRISING SILKWORM STORAGE PROTEIN 1 FOR PREVENTING OR TREATING ENDOPLASMIC RETICULUM STRESS-RELATED DISEASES

机译：1包含家蚕贮藏蛋白1的药物组合物，用于预防或治疗与网状应激相关的疾病

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摘要

The present invention relates to a pharmaceutical composition for preventing or treating endoplasmic reticulum stress-related diseases containing a storage protein 1 (SP1) of silkworms. Specifically, the storage protein 1 (SP1) of silkworms of the present invention inhibits ER Ca^(2+) release into cytoplasm and also inhibits the expression of CHOP and GRP78, thereby preventing and treating endoplasmic reticulum stress-related diseases.

机译：本发明涉及用于预防或治疗内质网应激相关疾病的药物组合物，其包含家蚕的贮藏蛋白1（SP1）。具体地，本发明的家蚕的贮藏蛋白1（SP1）抑制ER Ca ^（2+）释放到细胞质中，并且还抑制CHOP和GRP78的表达，从而预防和治疗内质网应激相关疾病。

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公开/公告号KR20190115285A

专利类型
公开/公告日2019-10-11

原文格式PDF
申请/专利权人 INCHEON UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION;
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申请/专利号KR20180038124
发明设计人 WON JONG RHEE;CHA YEONJU;
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申请日2018-04-02
分类号A61K35/64;A23L33/10;A23L33/17;A61P25/28;A61P3/10;
国家 KR
入库时间 2022-08-21 11:49:38

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