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3D 3D printing artificial trachea scaffold and manufacturing method thereof

机译:3d 3d打印人工气管支架及其制造方法

摘要

The present invention relates to a 3D printing artificial trachea scaffold and a manufacturing method thereof, and more particularly, to an artificial trachea scaffold capable of regenerating tracheal cartilage and tracheal mucosa using chondrocytes differentiated from patient-customized induced pluripotent stem cells and human-derived organ mucosal epithelial cells, and to a manufacturing method thereof. Since the artificial trachea scaffold, according to the present invention, has an excellent effect of regenerating cartilage and mucosal tissue simultaneously, the artificial trachea scaffold can reduce restenosis by improving mucous membrane regeneration related to maintenance of airway function and maintaining organ air ventilation in a long term. Thus, the artificial trachea scaffold of the present invention is expected to be very useful in treating organ defects and related diseases in tissue engineering and regenerative medicine fields.
机译:3D打印人工气管支架及其制造方法技术领域本发明涉及一种3D打印人工气管支架及其制造方法,更具体地说,涉及一种能够利用从患者定制的诱导多能干细胞和人源器官分化而来的软骨细胞再生气管软骨和气管粘膜的人工气管支架。粘膜上皮细胞及其制造方法。由于根据本发明的人工气管支架具有同时再生软骨和粘膜组织的优异效果,因此该人工气管支架可以通过改善与维持气道功能有关的粘膜再生并长期保持器官空气流通来减少再狭窄。术语。因此,预期本发明的人工气管支架在组织工程和再生医学领域中在治疗器官缺陷和相关疾病中非常有用。

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