首页> 外国专利> Composition for diagnosing lung cancer assaying drug response and prognosis through analysis of extracellular vesicle isolated from Bronchoalveolar lavage fluid

Composition for diagnosing lung cancer assaying drug response and prognosis through analysis of extracellular vesicle isolated from Bronchoalveolar lavage fluid

机译:通过分析从支气管肺泡灌洗液中分离的细胞外囊泡诊断肺癌的药物组合物和诊断方法

摘要

The present invention relates to a composition for diagnosis or prognosis prediction of lung cancer which analyzes extracellular endoplasmic reticulum isolated from bronchoalveolar lavage fluid of lung cancer patients, a kit for lung cancer diagnosis or prognosis prediction containing the composition, And a method of providing information. The method for detecting a mutation in a lung cancer expression gene using the bronchial alveolar lavage fluid according to the present invention is a non-invasive, easy, repeatable and highly sensitive method for detection of gene mutation through histological examination. It is easy to detect the cancer-causing mutation that occurs after. In addition, the extracellular endoplasmic reticulum derived from bronchoalveolar lavage fluid can analyze various information of DNA, RNA, protein, lipid and sugar biomolecule derived from cancer cells, thereby enabling accurate and efficient diagnosis. Therefore, Can contribute to the efficiency of lung cancer treatment.
机译:肺癌诊断或预后预测用组合物,分析该组合物的肺癌诊断或预后预测用试剂盒以及提供信息的方法,涉及对从肺癌患者的支气管肺泡灌洗液中分离出的细胞外内质网进行分析的肺癌的预后预测用组合物。根据本发明的使用支气管肺泡灌洗液检测肺癌表达基因中的突变的方法是通过组织学检查来检测基因突变的非侵入性,容易,可重复且高度灵敏的方法。很容易检测到之后发生的致癌突变。另外,源自支气管肺泡灌洗液的细胞外内质网可以分析源自癌细胞的DNA,RNA,蛋白质,脂质和糖类生物分子的各种信息,从而能够进行准确而有效的诊断。因此,可有助于提高肺癌的治疗效率。

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