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Composition for diagnosing lung cancer assaying drug response and prognosis through analysis of extracellular vesicle isolated from Bronchoalveolar lavage fluid
Composition for diagnosing lung cancer assaying drug response and prognosis through analysis of extracellular vesicle isolated from Bronchoalveolar lavage fluid
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机译:通过分析从支气管肺泡灌洗液中分离的细胞外囊泡诊断肺癌的药物组合物和诊断方法
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摘要
The present invention relates to a composition for diagnosis or prognosis prediction of lung cancer which analyzes extracellular endoplasmic reticulum isolated from bronchoalveolar lavage fluid of lung cancer patients, a kit for lung cancer diagnosis or prognosis prediction containing the composition, And a method of providing information. The method for detecting a mutation in a lung cancer expression gene using the bronchial alveolar lavage fluid according to the present invention is a non-invasive, easy, repeatable and highly sensitive method for detection of gene mutation through histological examination. It is easy to detect the cancer-causing mutation that occurs after. In addition, the extracellular endoplasmic reticulum derived from bronchoalveolar lavage fluid can analyze various information of DNA, RNA, protein, lipid and sugar biomolecule derived from cancer cells, thereby enabling accurate and efficient diagnosis. Therefore, Can contribute to the efficiency of lung cancer treatment.
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