首页> 外国专利> GLUCOSE REACTIVE COMPOSITE GEL COMPOSITION, METHOD FOR PRODUCING SAME, INSULIN DELIVERY MICRONEEDLE INCLUDING SAID GLUCOSE REACTIVE COMPOSITE GEL COMPOSITION, AND PRODUCING METHOD THEREFOR

GLUCOSE REACTIVE COMPOSITE GEL COMPOSITION, METHOD FOR PRODUCING SAME, INSULIN DELIVERY MICRONEEDLE INCLUDING SAID GLUCOSE REACTIVE COMPOSITE GEL COMPOSITION, AND PRODUCING METHOD THEREFOR

机译：葡萄糖反应性复合凝胶组合物，其制备方法，包含所谓的葡萄糖反应性复合凝胶组合物的胰岛素输送微球及其制备方法

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摘要

The present invention provides: a gel composition which can be preferably used for a microneedle that can release insulin in a self-regulated manner according to the concentration of glucose; and a microneedle using the same. An insulin delivery microneedle 1 has a base part 10 made from silk fibroin, at least one needle part 20 integrally provided on the base part 10, and an insulin reservoir 40. At least a tip portion of the needle part 20 comprises: a copolymer including a phenylboronic acid-based monomer unit; and a composite gel composition including a silk fibroin.

机译：本发明提供了一种凝胶组合物，其优选用于微针，该微针可以根据葡萄糖的浓度以自我调节的方式释放胰岛素。和使用相同的微针。胰岛素输送微针1具有：由丝素蛋白制成的基部10;至少一个一体地设置在基部10上的针部20;以及胰岛素储存器40。针部20的至少尖端部分包括：共聚物，包括基于苯基硼酸的单体单元;以及包含丝素蛋白的复合凝胶组合物。

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公开/公告号WO2019182099A1

专利类型
公开/公告日2019-09-26

原文格式PDF
申请/专利权人 NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY;KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY;
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申请/专利号WO2019JP12026
发明设计人 MATSUMOTO AKIRA;CHEN SIYUAN;
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申请日2019-03-22
分类号A61K9;A61K38/28;A61K47/34;A61K47/42;A61M37;A61P3/10;
国家 WO
入库时间 2022-08-21 11:53:07

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