Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors
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机译:靶向递送烟酰胺腺嘌呤二核苷酸挽救途径抑制剂
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摘要
Compounds and compositions are disclosed in which a NAMPT Drug Unit is linked to a targeting Ligand Unit through a Unit from which a NAMPT inhibitor compound or derivative thereof is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as cancer or an autoimmune disease, using the compounds and compositions of the invention are also disclosed.
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