首页> 外国专利> THERAPEUTIC HUMAN MAST CELLS, COMPOSITIONS, AND METHODS OF TREATING A TUMOR COMPRISING ADMINISTERING AUTOLOGOUS HUMAN MAST CELLS FROM ADIPOSE TISSUE

THERAPEUTIC HUMAN MAST CELLS, COMPOSITIONS, AND METHODS OF TREATING A TUMOR COMPRISING ADMINISTERING AUTOLOGOUS HUMAN MAST CELLS FROM ADIPOSE TISSUE

机译:脂肪组织治疗包含人自体造血干细胞的肿瘤的治疗性人类肥大细胞,组合物和方法

摘要

This disclosure is directed to mast cells obtained from adipose derived stem cells and sensitized with immunoglobulin-E targeted to a cancer antigen; compositions comprising mast cells obtained from adipose derived stem cells and sensitized with immunoglobulin-E targeted to a cancer antigen; and methods of treating a tumor in a subject, comprising administering to a subject a therapeutically effective amount of mast cells obtained from adipose derived stem cells, wherein the mast cells are autologous to the subject and sensitized with immunoglobulin-E targeted to a cancer antigen.
机译:本公开涉及获自脂肪来源的干细胞并用靶向癌症抗原的免疫球蛋白-E致敏的肥大细胞;组合物,其包含获自脂肪干细胞并用靶向癌症抗原的免疫球蛋白-E致敏的肥大细胞;以及在受试者中治疗肿瘤的方法,其包括向受试者施用治疗有效量的从脂肪衍生的干细胞获得的肥大细胞,其中所述肥大细胞对受试者是自体的,并用靶向癌症抗原的免疫球蛋白-E敏化。

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