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ENZYMES AND METHODS FOR THE STEREOSELECTIVE REDUCTION OF CARBONYL COMPOUNDS, OXIDATION AND STEREOSELECTIVE REDUCTIVE AMINATION - FOR THE ENANTIOSELECTIVE PREPARATION OF ALCOHOL AMINE COMPOUNDS
ENZYMES AND METHODS FOR THE STEREOSELECTIVE REDUCTION OF CARBONYL COMPOUNDS, OXIDATION AND STEREOSELECTIVE REDUCTIVE AMINATION - FOR THE ENANTIOSELECTIVE PREPARATION OF ALCOHOL AMINE COMPOUNDS
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机译:用于立体选择性还原羰基化合物,氧化和立体选择性还原胺化的酶和方法-对映体制备醇胺化合物
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摘要
The invention relates to enzymes for use in a method for the stereoselective reduction of carbonyl compounds or oxidation of hydroxy compounds, in a method for isomerization between ephedrine and pseudoephedrine, and in a method for the stereoselective reductive amination of chiral alpha-hydroxy ketones to obtain an amine as well as the counterreaction. Also disclosed are the amino acid sequence of said enzymes, fusion proteins comprising the enzyme, and a vector, cell or organism containing a nucleotide sequence coding for the enzyme. Further disclosed are the corresponding methods and the use in said methods.
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