ANTISENSE OLIGONUCLEOTIDE DIRECTED REMOVAL OF PROTEOLYTIC CLEAVAGE SITES FROM PROTEINS.

• 1. 靶向SMN2启动子区甲基化位点nt-290所在区域的反义寡核苷酸 [P] . 中国专利： CN112662671A . 2021-04-16
• 2. 确定多位点PEG修饰蛋白质修饰位点的分析方法 [P] . 中国专利： CN110118847B . 2021.08.10
• 3. ANTISENSE OLIGONUCLEOTIDE DIRECTED REMOVAL OF PROTEOLYTIC CLEAVAGE SITES FROM PROTEINS. [P] . CA2807187A1 . 2012-02-09

  机译： 将反义寡核苷酸直接从蛋白质中去除了蛋白水解位点。

• 4. ANTISENSE OLIGONUCLEOTIDE DIRECTED REMOVAL OF PROTEOLYTIC CLEAVAGE SITES, THE HCHWA-D MUTATION, AND TRINUCLEOTIDE REPEAT EXPANSIONS [P] . 美国专利： US2020224203A1 . 2020-07-16

  机译： 反义寡核苷酸可直接去除蛋白裂解位点，HCHWA-D突变和三核苷酸重复扩展

• 5. ANTISENSE OLIGONUCLEOTIDE DIRECTED REMOVAL OF PROTEOLYTIC CLEAVAGE SITES FROM PROTEINS [P] . 美国专利： US2020332298A1 . 2020-10-22

  机译： 从蛋白质中去除蛋白质的蛋白质裂解位点的反义寡核苷酸

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• 5. Therapeutic Modulation of DMD Splicing by Blocking Exonic Splicing Enhancer Sites with Antisense Oligonucleotides [C] . A.AARTSMA-RUS, A.A.M.JANSON, J.A.HEEMSKERK, Oligonucleotide Therapeutics Society . 2006
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• 8. Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation. [O] . T. Saison-Behmoaras, B. Tocqué, I. Rey, 1991

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