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TREATMENT OF ADVANCED HER2 EXPRESSING CANCER.

机译:先进的HER2表达癌的治疗。

摘要

Methods for the treatment of patients with HER2-positive, HER2-amplified and/or HER2-mutated advanced cancer by administration of pertuzumab plus trastuzumab are disclosed. In one aspect, the cancer is advanced HER2-positive, HER2-amplified and/or HER2-mutated colorectal, biliary, bladder, urothelial, salivary, lung, pancreatic, ovarian, prostate, or skin cancer. In another aspect, the cancer is HER2-positive, HER2-amplified and/or HER2-mutated colorectal, biliary, bladder, urothelial, salivary, lung, pancreatic, ovarian, prostate, or skin cancer that is refractory to one or more other treatment regimens.
机译:公开了通过给予帕妥珠单抗加曲妥珠单抗治疗HER2阳性,HER2扩增和/或HER2突变的晚期癌症患者的方法。一方面,该癌症是晚期HER2阳性,HER2扩增和/或HER2突变的结直肠癌,胆道癌,膀胱癌,尿路上皮癌,唾液癌,肺癌,胰腺癌,卵巢癌,前列腺癌或皮肤癌。在另一方面,该癌症是对一种或多种其他治疗难以治疗的HER2阳性,HER2扩增和/或HER2突变的结直肠癌,胆道癌,膀胱癌,尿路上皮癌,唾液癌,肺癌,胰腺癌,卵巢癌,前列腺癌或皮肤癌。养生方法。

著录项

  • 公开/公告号MX2019007801A

    专利类型

  • 公开/公告日2019-10-30

    原文格式PDF

  • 申请/专利权人 GENENTECH INC.;

    申请/专利号MX20190007801

  • 发明设计人 MARY BEATTIE;MELISSA BRAMMER;

    申请日2017-12-14

  • 分类号A61K39/395;A61P35/04;C07K16/32;

  • 国家 MX

  • 入库时间 2022-08-21 12:01:44

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