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APPLICATION OF ADAMTS13 FOR TREATMENT, REDUCING THE INTENSITY AND / OR PREVENTION OF A VASA-OCCLUSIVE CRISIS WITH Sickle-cell anemia, ACUTE DAMAGE TO LIGHT AND / OR ACUTE RESPIRATOR-DYNESIS
APPLICATION OF ADAMTS13 FOR TREATMENT, REDUCING THE INTENSITY AND / OR PREVENTION OF A VASA-OCCLUSIVE CRISIS WITH Sickle-cell anemia, ACUTE DAMAGE TO LIGHT AND / OR ACUTE RESPIRATOR-DYNESIS
The present disclosure relates to compositions and a method for treating, reducing the intensity or preventing vaso-occlusive crisis (VOC) in a subject suffering from sickle cell anemia (SCD). The present disclosure also relates to compositions and methods for treating, reducing the intensity or preventing lung damage in a subject suffering from acute lung injury (ALI) and / or acute respiratory distress syndrome (ARDS) or at risk of developing them. The present disclosure relates to a disintegrin and metalloproteinase with a thrombospondin type 1 motif 13 (A Disintegrin And Metalloproteinase with Thrombospondin type 1 motif, member-13-ADAMTS13) or a composition containing ADAMTS13 for the treatment, reduction of intensity and / or prevention of VOC or for treating, reducing the intensity and / or preventing lung damage in a subject suffering from ALI and / or ARDS or at risk of developing.
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