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METHOD FOR DIFFERENTIAL DIAGNOSTICS OF ANEMIA ASSOCIATED WITH DIFFUSE TOXIC GOITER

机译:弥散性毒性血栓相关性贫血的鉴别诊断方法

摘要

The invention relates to medicine, in particular, to laboratory diagnostic methods, and is intended for identifying a diagnostic marker of anemia development against the background of diffuse toxic goiter (DTG). The essence of the invention consists in provision of a method for diagnosing anemia associated with DTG, comprising immunological blood study and assessment of a diagnostic marker for anemia, which is presented by erythrophagocytosis assay making it possible to establish the participation of autoimmune factors in anemia development based on the reaction of erythrocyte absorption by neutrophils, and if erythrophagocytosis so assessed exceeds 1%, anemia development is diagnosed. The claimed invention widens the list of anemia diagnostic markers, which makes it possible to improve accuracy of the diagnostics.
机译:本发明涉及医学,特别是涉及实验室诊断方法,并旨在鉴定以弥散性毒性甲状腺肿(DTG)为背景的贫血发展的诊断标志物。本发明的实质在于提供一种诊断与DTG相关的贫血的方法,该方法包括对血液的免疫学研究和对贫血的诊断标志物的评估,其由红细胞吞噬作用测定法提出,从而有可能建立自身免疫因子参与贫血发展的过程。根据中性粒细胞吸收红细胞的反应,如果评估的红细胞吞噬作用超过1%,则可诊断为贫血。所要求保护的发明扩大了贫血诊断标志物的范围,这使得可以提高诊断的准确性。

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